Tooth-Supporting Hard Tissue Regeneration Using Biopolymeric Material Fabrication Strategies

Tooth tissue and organ regeneration using stem cells

Tooth loss or damage, such as that caused by dental caries and periodontal disease, can cause fundamental problems with oral functions. The development of regenerative therapy for tooth tissue repair and whole-tooth replacement is currently considered a novel treatment with the potential to fully recover tooth function. Several mesenchymal stem cell-like cell types have been identified in oral ...

Whole Tooth Regeneration Using a Bioengineered Tooth

Gene-enhanced tissue engineering for dental hard tissue regeneration: (2) dentin-pulp and periodontal regeneration

Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in dental and craniofacial reconstruction. Part 1 reviewed the principals of gene-enhanced tissue engineering and the techniques of introducing DN...

Autogenous tooth transplantation: evaluation of pulp tissue regeneration.

OBJECTIVE The aim of this study was to assess the pulp survival that occur in transplants of autologous teeth, by comparing two surgical techniques: the conventional technique (autotransplantation for newly formed alveoli), and an alternative technique, (autotransplants for alveoli in the initial phase of healing). In each surgical techniques were applied, randomly, either saline solution or Em...

Dental Cell-ECM Interactions in Tooth Tissue Regeneration

Introduction Tooth loss remains a significant health problem even in developed countries such as the United States. Our research focuses on the development of non-synthetic, bioengineered materials for dental and craniofacial tissue engineering. We hypothesize that dental stem cells harvested from extracted teeth provides a potential source for human progenitor cells for tissue engineering. Our...